Description
Botulinum toxin
The term botulinum toxin peptide can refer to the structural peptide chains that make up the active Botulinum Toxins neurotoxin protein, synthetic cosmetic "botox-like" topical peptides, or specific peptide fragments used in laboratory testing and FRET assays
Laboratory Research Data Analysis
- Native botulinum neurotoxins are large proteins (150 kDa) synthesized as a single peptide chain before being cleaved into a heavy chain and a light chain joined by a disulfide bond
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Enzymatic Action: The light chain acts as a zinc-dependent endopeptidase that targets and cuts specific SNARE proteins (like SNAP-25) inside nerve endings to stop acetylcholine release and cause muscle relaxation.


