{"product_id":"p-21","title":"P-21","description":"\u003ch4 style=\"text-align: left;\"\u003e\u003cstrong\u003e\u003cspan style=\"color: #00e2ff;\"\u003eP-21\u003c\/span\u003e\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cdiv class=\"n6owBd awi2gc\" style=\"text-align: left;\"\u003e\n\u003cp class=\"PDq2pG_selectionAnchorContainer\"\u003ePeptide 021 (Ac-DGGLAG-NH2, P021, GLXC-21260) is a synthetic peptide derivative that is derived from a 4-amino acid active fragment of ciliary neurotrophic factor, which has been substituted with an unnatural adamantane based amino acid residue on the end of the chain. This substitution is highly lipophilic and facilitates transport of the molecule across the blood-brain barrier. It has neurotrophic effects and enhances neurogenesis, and has been investigated for treatment of neurological disorders such as Alzheimer's disease\u003c\/p\u003e\n\u003cbr\u003e\u003c!--TgQPHd|[]--\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"n6owBd awi2gc\" style=\"text-align: left;\"\u003e\n\u003ch4 id=\"laboratory-research-data-analysis\"\u003e\u003cspan style=\"color: rgb(0, 226, 255);\"\u003e\u003cspan class=\"gs_tkn\"\u003eLaboratory \u003c\/span\u003e\u003cspan class=\"gs_tkn\"\u003eResearch \u003c\/span\u003e\u003cspan class=\"gs_tkn\"\u003eData \u003c\/span\u003e\u003cspan class=\"gs_tkn\"\u003eAnalysis\u003c\/span\u003e\u003c\/span\u003e\u003c\/h4\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"\"\u003e\n\u003cul style=\"margin-top: 0cm;\" type=\"disc\"\u003e\n\u003cli style=\"text-align: left; font-style: italic;\"\u003e28-amino-acid neuropeptide\u003c\/li\u003e\n\u003cli style=\"text-align: left; font-style: italic;\"\u003eDerived from the prepro-orexin precursor\u003c\/li\u003e\n\u003cli style=\"text-align: left; font-style: italic;\"\u003eOne of two orexin peptides: Orexin A and Orexin B\u003c\/li\u003e\n\u003cli style=\"text-align: left; font-style: italic;\"\u003eInteracts primarily with the OX2 orexin receptor (OX2R)\u003c\/li\u003e\n\u003cli style=\"text-align: left; font-style: italic;\"\u003eInvolved in neuronal signalling and arousal pathways\u003c\/li\u003e\n\u003cli style=\"text-align: left; font-style: italic;\"\u003eStudied in neuroscience and neurobiology research\u003c\/li\u003e\n\u003cli style=\"text-align: left; font-style: italic;\"\u003eInvestigated in relation to energy-balance and metabolic signalling\u003c\/li\u003e\n\u003cli style=\"text-align: left; font-style: italic;\"\u003eCell-based assays: analysis of receptor activity and cellular signalling\u003c\/li\u003e\n\u003cli style=\"text-align: left; font-style: italic;\"\u003eUsed in research examining orexin receptor activation and downstream pathways\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003c\/div\u003e","brand":"Bionik Peptides","offers":[{"title":"Default Title","offer_id":59190113403225,"sku":"BP-5081-P-2-BIO-DEF","price":0.0,"currency_code":"GBP","in_stock":false}],"url":"https:\/\/bionikpeptides.com\/products\/p-21","provider":"Bionik Peptides","version":"1.0","type":"link"}