{"product_id":"demorphin","title":"Demorphin (Dermorphin)","description":"\u003ch4 style=\"text-align: left;\"\u003e\u003cstrong\u003e\u003cspan style=\"color: #00e2ff;\"\u003eDomorphin\u003c\/span\u003e\u003c\/strong\u003e\u003c\/h4\u003e\n\u003cdiv class=\"n6owBd awi2gc\" style=\"text-align: left;\"\u003e\n\u003cp id=\"mwBg\"\u003e\u003cspan style=\"color: rgb(128, 128, 128);\"\u003eDermorphin is a hepta-\u003ca rel=\"mw:WikiLink\" href=\"https:\/\/en.wikipedia.org\/wiki\/Peptide\" title=\"Peptide\" id=\"mwCA\" style=\"color: rgb(128, 128, 128);\"\u003epeptide\u003c\/a\u003e first isolated from the skin of South American \u003ca rel=\"mw:WikiLink\" href=\"https:\/\/en.wikipedia.org\/wiki\/Frog\" title=\"Frog\" id=\"mwCQ\" style=\"color: rgb(128, 128, 128);\"\u003efrogs\u003c\/a\u003e belonging to the genus \u003ci id=\"mwCg\"\u003ePhyllomedusa\u003c\/i\u003e.  The peptide is an agonist with high potency and selectivity to mu opioid receptors. Dermorphin is about 30–40 times more potent than morphine.\u003csup class=\"mw-ref reference\" id=\"cite_ref-4\" rel=\"dc:references\"\u003e\u003c\/sup\u003e The amino acid sequence of dermorphin is H-Tyr-\u003csmall id=\"mwHw\"\u003eD\u003c\/small\u003e-Ala-Phe-Gly-Tyr-Pro-Ser-NH\u003csub id=\"mwIA\"\u003e2\u003c\/sub\u003e.\u003c\/span\u003e\u003c\/p\u003e\n\u003cp id=\"mwIQ\"\u003e\u003cspan style=\"color: rgb(128, 128, 128);\"\u003eDermorphin is not found in humans or other mammals and similar D-amino acid containing peptides have only been found in bacteria, amphibians, and molluscs.\u003csup class=\"mw-ref reference\" id=\"cite_ref-5\" rel=\"dc:references\"\u003e\u003c\/sup\u003e Dermorphin appears to be made via the posttranslational modification of a precursor peptide by an amino acid isomerase.\u003csup class=\"mw-ref reference\" id=\"cite_ref-6\" rel=\"dc:references\"\u003e\u003ca href=\"https:\/\/en.wikipedia.org\/wiki\/Dermorphin#cite_note-6\" id=\"mwLA\" style=\"color: rgb(128, 128, 128);\"\u003e\u003cspan class=\"mw-reflink-text\" id=\"mwLQ\"\u003e\u003cspan class=\"cite-bracket\" id=\"mwLg\"\u003e[\u003c\/span\u003e6\u003cspan class=\"cite-bracket\" id=\"mwLw\"\u003e]\u003c\/span\u003e\u003c\/span\u003e\u003c\/a\u003e\u003c\/sup\u003e This unusual process is needed because the \u003csmall id=\"mwMA\"\u003eD\u003c\/small\u003e-alanine in this peptide is not part of the standard genetic code.\u003c\/span\u003e\u003c\/p\u003e\n\u003cbr\u003e\u003c!--TgQPHd|[]--\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"n6owBd awi2gc\" style=\"text-align: left;\"\u003e\n\u003ch4 id=\"laboratory-research-data-analysis\"\u003e\u003cspan style=\"color: rgb(0, 226, 255);\"\u003e\u003cspan class=\"gs_tkn\"\u003eLaboratory \u003c\/span\u003e\u003cspan class=\"gs_tkn\"\u003eResearch \u003c\/span\u003e\u003cspan class=\"gs_tkn\"\u003eData \u003c\/span\u003e\u003cspan class=\"gs_tkn\"\u003eAnalysis\u003c\/span\u003e\u003c\/span\u003e\u003c\/h4\u003e\n\u003c\/div\u003e\n\u003cdiv class=\"\"\u003e\n\u003cul style=\"margin-top: 0cm;\" type=\"disc\"\u003e\n\u003cli style=\"text-align: left; font-style: italic;\"\u003e\n\u003cstrong class=\"rQesXe MPyX\" style=\"font-family: Google Sans, Arial, sans-serif; font-size: 16px; font-weight: bold; margin: 0px; text-decoration: none; border-bottom: 0px rgb(10, 10, 10);\"\u003eSequence:\u003c!--TgQPHd|||[]--\u003e\u003c\/strong\u003e Tyr-D-Ala-Phe-Gly-Tyr-Pro-Ser-NH2\u003c\/li\u003e\n\u003cli style=\"text-align: left; font-style: italic;\"\u003e\n\u003cstrong class=\"rQesXe MPyX\" style=\"font-family: Google Sans, Arial, sans-serif; font-size: 16px; font-weight: bold; margin: 0px; text-decoration: none; border-bottom: 0px rgb(10, 10, 10);\"\u003eCAS Number:\u003c!--TgQPHd|||[]--\u003e\u003c\/strong\u003e 77614-16-5\u003c\/li\u003e\n\u003cli style=\"text-align: left; font-style: italic;\"\u003e\n\u003cstrong class=\"rQesXe MPyX\" style=\"font-family: Google Sans, Arial, sans-serif; font-size: 16px; font-weight: bold; margin: 0px; text-decoration: none; border-bottom: 0px rgb(10, 10, 10);\"\u003eMolecular Formula:\u003c!--TgQPHd|||[]--\u003e\u003c\/strong\u003e C40H50N8O10\u003c\/li\u003e\n\u003cli style=\"text-align: left; font-style: italic;\"\u003e\n\u003cstrong class=\"rQesXe MPyX\" style=\"font-family: Google Sans, Arial, sans-serif; font-size: 16px; font-weight: bold; margin: 0px; text-decoration: none; border-bottom: 0px rgb(10, 10, 10);\"\u003ePurity:\u003c!--TgQPHd|||[]--\u003e\u003c\/strong\u003e Typically ≥ 98% (HPLC verified)\u003c\/li\u003e\n\u003c\/ul\u003e\n\u003cp style=\"text-align: left;font-style: italic;\"\u003e \u003c\/p\u003e\n\u003cp style=\"text-align: left;font-style: italic;\"\u003e \u003c\/p\u003e\n\u003cp style=\"text-align: left; font-style: italic;\"\u003e\u003cimg src=\"https:\/\/cdn.shopify.com\/s\/files\/1\/1040\/2005\/0265\/files\/Dermorphin_svg.webp?v=1787863051\" alt=\"\" width=\"675\" height=\"221\"\u003e\u003c\/p\u003e\n\u003c\/div\u003e","brand":"Bionik Peptides","offers":[{"title":"2mg","offer_id":59187719864665,"sku":null,"price":30.0,"currency_code":"GBP","in_stock":false}],"thumbnail_url":"\/\/cdn.shopify.com\/s\/files\/1\/1040\/2005\/0265\/files\/Demorphin.png?v=1787872748","url":"https:\/\/bionikpeptides.com\/products\/demorphin","provider":"Bionik Peptides","version":"1.0","type":"link"}